Sirtuin 1 overexpression in mice preserves insulin and thermogenic responses in subcutaneous inguinal white adipose tissue under proinflammatory conditions.

Moreover, Ucp1 mRNA levels showed a trend to an increase in iWAT from Sirt1 Tg+ mice compared to WT mice, an effect that was more evident in UCP-1 protein levels as shown by Western blot and IHC (Fig. 1 b).

also in 53,322 other papers