Adenoviral vector oropharyngeal spray immunization elicits mucosal immunity and protects against heterologous SARS-CoV-2 infection.

NPJ Vaccines · 2025 · PMC12739146 · PMID 41390777

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did not reach statistical significanceno p-value reported

Due to high variation in virus production in the nose, with one Ad5 boosted animal being virus positive and one control animal being virus negative, this comparison did not reach statistical significance.

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