Barely Significant
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Validating the cortisol hypothesis: Xanamem demonstrates positive clinical effects by lowering CNS cortisol

Alzheimers Dement · 2025 · PMC12741215

Europe PMC
1
hedged sentence
0.0800
closest p · 1.6× alpha
0.0800
boldest claim

The sentences

showed a trendp=0.08so close (0.05 < p ≤ 0.1)
Xanamem showed a trend towards higher response rates at Week 10 (50% MADRS reduction, 34% Xanamem vs. 22% placebo, p=0.08).

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