Rational Design of Metal-Organic Frameworks for Pancreatic Cancer Therapy: from Machine Learning Screening to In Vivo Efficacy.

Adv Mater · 2025 · PMC12747470 · PMID 39895194

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slightly significantno p-value reported

HA‐based hydrogels containing nanoparticles such as MOF are an efficient local delivery strategy, having prolonged contact with abdominal organs, reducing off‐target effects, and endowing a slightly significant tumor reduction on hydrogels containing the PEG@Pac@PCN‐222 formulation.

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