highly significantP < 0.0001
Ordinary one-way ANOVA showed highly significant differences among the four severity groups for all three proteins (all P < 0.0001).
Ordinary one-way ANOVA showed highly significant differences among the four severity groups for all three proteins (all P < 0.0001).
3.2 IL-18 receptor components are selectively upregulated in allergic NK and T cells In a public scRNA-seq dataset from an AC mouse model, the Il18r1 homolog of the IL-18 receptor was significantly upregulated in conjunctival tissue of allergy-model mice compared with controls (avg_log2FC = 1.15, P-adj = 0.02657758), while Il18rap (the accessory protein) showed a trend towards increased expression ( Table 2 ).