A lightweight cerebrospinal fluid biomarker-based model for first-diagnosis prediction of Parkinson's disease: model development, external validation, and local deployment.

Front Aging Neurosci · 2025 · PMC12748221 · PMID 41477166

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did not reach statistical significanceno p-value reported

Aβ42, t-tau, p-tau181, and hemoglobin did not reach statistical significance in the multivariable model, underscoring that their individual effects are limited when modeled jointly with α-syn.

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