Comparative effects of fentanyl, morphine, and hydromorphone on postoperative delirium and outcomes after cardiac surgery: a propensity score-matched cohort study.

Sci Rep · 2025 · PMC12749987 · PMID 41309996

Europe PMC DOI

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0.1920

closest p · 3.8× alpha

0.1920

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did not reach statistical significancep = 0.192not close (p > 0.1)

We directly compared the effects of hydromorphone and morphine on POD risk to the potential impact of CPB-OHS.As Table S4 shows, in a multivariate model, hydromorphone’s OR was 0.82 (95% CI 0.60–1.11), which did not reach statistical significance ( p = 0.192).

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