Barely Significant
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Cerebrospinal fluid NPTX2 and [<sup>18</sup>F]FDG PET track serotonergic vulnerability to neurodegeneration in prodromal Alzheimer's disease.

Alzheimers Res Ther · 2025 · PMC12750555 · PMID 41272913

1
hedged sentence
0.0650
closest p · 1.3× alpha
0.0650
boldest claim

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showed a trendp = 0.065so close (0.05 < p ≤ 0.1)
In the post hoc analysis, the correlation between NPI scores and CSF NPTX2 levels showed a trend toward a negative association ( r = − 0.27, p = 0.065), without reaching statistical significance.

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