17β-estradiol mediates sex-biased progesterone receptor expression via estrogen receptor α in chicken pituitary.

Poult Sci · 2026 · PMC12752528 · PMID 41380332

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

did not reach statistical significancep = 0.06so close (0.05 < p ≤ 0.1)

qRT-PCR analysis revealed that 10 nM E 2 upregulated PGR expression, though this effect did not reach statistical significance ( p = 0.06).

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highly significantno p-value reported

However, this hypothesis remains to be validated, and its confirmation would represent a highly significant and compelling avenue for further investigation.

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