RELA Ablation Contributes to Progression of Hepatocellular Carcinoma with TP53<sup>R249S</sup> Mutation and is a Potential Therapeutic Target.

Interestingly, low mRNA expression of RELA showed a trend toward poor prognosis in all HCC patients (HR = 0.84) (Figure S3A , Supporting Information) and was significantly associated with worse outcomes in early‐stage patients or those with high differentiation (Grade 2, HR = 0.53; Grade 2 and Stage 1 + 2, HR = 0.29) ( Figure 2 A ).

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