In the OS analysis, while a trend towards poorer survival was observed in patients with elevated HCCS expression, the association did not reach statistical significance ( n = 1879, HR = 0.9 [0.9–1.31], p = 0.4) (Figure 6a ).
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HCCS Serves as Potential Prognostic Biomarker and Therapeutic Target in Human Breast Cancer.
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Gene Set Enrichment Analysis of HCCS‐correlated Genes Enrichment analysis of the 11 HCCS‐correlated genes, identified from a PPI network analysis (Figure S4), revealed a highly significant and coherent set of biological functions, processes, and pathways, primarily centered on mitochondrial heme metabolism and oxidative phosphorylation (Table S1).