Properties, Origin, and Consistency of Truncated Proteoforms Across Top-Down Proteomic Studies.

Mol Cell Proteomics · 2025 · PMC12753228 · PMID 41237901

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a clear trendno p-value reported

Consequently, study designs that increase overall sensitivity, such as utilizing multidimensional liquid-based or online gas-phase–based fractionation schemes, also show a clear trend toward the identification of an increased number of truncated proteoforms.

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