Human epidermal Langerhans cells induce tolerance and hamper T cell function upon tick-borne pathogen transmission.

Nat Commun · 2025 · PMC12753675 · PMID 41315257

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The numbers of CD69 + tissue resident memory T cells (Trm) did not change significantly, but showed a trend towards an increase when co-cultured with SGE-stimulated moLCs similar to what we previously observed in an experimental tick bite model 5 .

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