N-palmitoyl glycine differentially modulates TRPM4 and TRPC5 and is causally linked to Brugada syndrome.

Commun Biol · 2025 · PMC12753829 · PMID 41315851

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nominally significantno p-value reported

IGFBP3 increases the risk of BrS and is mediated by N-palmitoyl glycine A total of 69 circulating metabolites were nominally significant, and only one metabolite (N-palmitoyl glycine, PalGly) reached the Bonferroni-corrected threshold ( p < 0.05/1190) (Supplementary Data 9 ).

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