Gut microbiota-derived trimethylamine N-oxide exacerbates diabetic nephropathy by promoting renal fibrosis.

World J Nephrol · 2025 · PMC12754428 · PMID 41479812

Europe PMC DOI

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did not reach statistical significanceP > 0.05actually significant

Although Masson staining results did not reach statistical significance ( P > 0.05), notable alterations in intestinal flora structure were observed in DN rats, and fecal microbiota transplantation led to increased TMAO production within the intestinal flora of DN rats compared to controls ( P > 0.05).

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