Propofol exerted the neuroprotective effects by regulating renin-angiotensin system and mitochondria-associated endoplasmic reticulum membrane in the postoperative cognitive dysfunction.

BMC Anesthesiol · 2025 · PMC12754873 · PMID 41275108

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did not reach statistical significanceno p-value reported

Lower Ang II levels were detected in the propofol group compared to the control group,, though this difference did not reach statistical significance, whereas higher Ang II levels were observed in the other anesthetic groups (isoflurane, sevoflurane, chloral hydrate, and pentobarbital sodium) relative to the control group (Fig. 3 A).

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