Integrative analysis of gene expression and histone modifications for DES, DSP, GJA1 and SMOC2 in adipose tissue reveals potential relationship to cardiometabolic health.

Mol Med · 2025 · PMC12754950 · PMID 41275133

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did not reach statistical significanceno p-value reported

In a second cohort consisting of individuals with morbid obesity undergoing a two-step bariatric surgery (BSC; N = 65) aimed at weight loss, DES , DSP , and SMOC2 were successfully validated with significant higher expression in OVAT compared to SAT, while GJA1 did not reach statistical significance (Fig. 2 B).

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