Barely Significant
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Identification of plasma hsa_circ_0000190 and 0001649 as biomarkers for predicting the recurrence and treatment response of patients with oral squamous cell carcinoma.

J Chin Med Assoc · 2022 · PMC12755481 · PMID 35125403

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hedged sentences
0.0001
closest p · 0.0× alpha
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boldest claim

The sentences

highly significantp < 0.0001actually significant
We found that the plasma levels of hsa_circ_0000190 and 0001649 in OSCC patients were downregulated compared to that in healthy individuals, with a highly significant decrease ( p < 0.0001) of hsa_circ_0000190 in the late stage (Fig. 2 A).

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Notably, the tendency for patients with low levels of both hsa_circ_0000190 and 0001649 to have a worse overall survival did not reach statistical significance, likely due to the small number of cases (Fig. 4 , right).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.