Copy number variants in fetuses with isolated and non-isolated increased nuchal translucency detected by chromosomal microarray analysis.

Front Genet · 2025 · PMC12755859 · PMID 41480154

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an increasing trendno p-value reported

In fetuses with isolated increased NT, with the increase of NT thickening, the rate of chromosomal aneuploidy shows an increasing trend.

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did not reach statistical significanceno p-value reported

Notably, the difference in detection performance between the two sample types did not reach statistical significance in this study, which may be attributed to the adequate sample size and the strict exclusion of cases suspected of placental mosaicism.

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