SMAC mimetics sensitize HIV-infected cells to oncolytic virus-mediated death.

Although there was a significant increase in annexin-V-expressing HSA+ cells that were treated with birinapant and MG1 in comparison to cells treated with birinapant alone, this increase in annexin V+ cells did not quite reach significance ( p = 0.0596) ( Figure 5C ) when compared with the cells only treated with MG1.

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Although there was a trend in decreasing proviral DNA in the MDMs treated with the SMAC mimetics and MG1, this difference did not reach statistical significance when compared with the cells only infected with MG1 ( Figure 5D ).

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