Mechanosensitive Yes-Associated Protein/TAZ-cGAS-STING Axis Induces Periodontal Ligament Fibroblasts Senescence and Mediates Compression-Induced Root Resorption.

Int Dent J · 2026 · PMC12757478 · PMID 41385921

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Furthermore, after XMU-MP-1 treatment, the expression of senescence markers, such as P21 and γ-H2AX, decreased, while continued treatment with c-di-GMP showed a trend of enhanced senescent phenotypes ( Figure 4 H,I).

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