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Endogenous tetrahydrobiopterin in humans: circadian rhythm, sex, race, age, and disease status.

Front Pharmacol · 2025 · PMC12757610 · PMID 41487510

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a clear trendno p-value reported
Nevertheless, median BH 4 still illustrated a clear trend with circadian rhythm.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.