Broadly neutralizing antibody responses in a Chinese acute HIV-1 infection cohort of men who have sex with men.

PLoS Pathog · 2026 · PMC12758743 · PMID 41481608

Europe PMC DOI

hedged sentence

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closest p · 1.4× alpha

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boldest claim

The sentences

did not reach statistical significanceP = 0.07so close (0.05 < p ≤ 0.1)

In univariate analysis, acquisition of a second strain beyond one year after primary infection was significantly associated with enhanced bnAb responses (OR = 17.40, 95% CI: 1.75–172.62, P = 0.02; Table 2 ), while acquisition within one year showed a borderline association that did not reach statistical significance (OR = 5.80, 95% CI: 0.87–38.46, P = 0.07).

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