Picolinic acid, a tryptophan metabolite, exhibits anabolic effects in muscle cells and improves lifespan and movement in C. elegans.

J Gerontol A Biol Sci Med Sci · 2026 · PMC12758968 · PMID 41191737

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showed a trendp = .060so close (0.05 < p ≤ 0.1)

At day 5, murine cells showed a trend toward an increased fusion index with 1 (Δ = 4.9%; p = .060) and 50 μM (Δ = 4.8%; p = .075), but not with 100 μM (Δ = 2.8%; p = .869).

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