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Uncoupling Insulin Sensitivity From Longevity: A Sex-Dependent Effect of Hepatic Glucagon Signaling.

Aging Cell · 2026 · PMC12759044 · PMID 41482628

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Female LKO mice also displayed reduced maximal survival at the 75th percentile of life (although 90th percentile survival did not reach statistical significance) while no change was observed in males.

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