Long Life Family Study Participants Carry Rare Variants That Correlate With Better Cognitive Function

Innov Aging · 2025 · PMC12762697

Europe PMC

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nominally significantno p-value reported

We then compared results with UK Biobank GWAS of general cognitive ability and reaction time, conducted quantitative trait locus (QTL) analyses of whole blood transcriptomic and serum metabolomic data for genome-wide significant variants (p < 5e-8), and performed gene set enrichment analyses of nominally significant transcripts.

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