Effect of dexmedetomidine on postoperative mortality and prognosis: a systematic review and meta-analysis of randomized controlled trials.

BMC Anesthesiol · 2025 · PMC12764088 · PMID 41286611

Europe PMC DOI

hedged sentence

0.1800

closest p · 3.6× alpha

0.1800

boldest claim

The sentences

did not reach statistical significanceP = 0.18not close (p > 0.1)

4 ).A significant reduction was observed in patients undergoing cardiac surgery (RR 0.39, 95% CI 0.18–0.85; P = 0.02), whereas no significant benefit was detected in non-cardiac surgical patients (RR 0.73, 95% CI 0.38–1.41; P = 0.34), although the test for subgroup differences did not reach statistical significance ( P = 0.18).

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