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Immune Checkpoint-Related Gene Polymorphisms and High Serum Concentration of PD-L1 and CTLA4 Contribute to the Resistance to Platinum-Based Chemotherapy in Cervical Cancer.

Int J Womens Health · 2025 · PMC12764211 · PMID 41488765

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In adenocarcinoma patients, the association between the PDCD1 -rs2227982 polymorphism and platinum-based chemotherapy resistance did not reach statistical significance under the genotypic, recessive, or additive models.

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