Efficacy and safety of sequential versus concurrent administration of immune checkpoint inhibitors with radiotherapy in solid tumors: a systematic review and network meta-analysis.

Cancer Immunol Immunother · 2026 · PMC12764719 · PMID 41484398

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showed a trendno p-value reported

The sequential ICI arm showed a trend toward improved OS compared with the concurrent ICI arm, although the result was not significant (HR: 0.85 [95% CI 0.72 to 1.00]; Fig. 3 a and Supplementary Fig. 1a).

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