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Single-cell transcriptomic analysis reveals distinct cancer-associated fibroblast signatures in treatment-refractory esophageal squamous cell carcinoma.

Sci Rep · 2025 · PMC12764871 · PMID 41345494

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In tumor regions, the presence group showed higher fibroblast proportions (mean 52.86%) compared to the absence group (mean 29.29%), although this difference did not reach statistical significance.

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