Clinical and Histopathological Outcomes of High-Purity Type I Collagen in Chronic Wounds: A Systematic Review of Four Randomized Controlled Trials.

Cureus · 2026 · PMC12765199 · PMID 41492329

Europe PMC DOI

hedged sentence

—

closest p

—

boldest claim

The sentences

did not reach statistical significanceno p-value reported

Pressure ulcers showed similar trends, with 75% closure in HPTC-treated wounds versus 62.5% in the dHACM cohort, but this difference did not reach statistical significance [ 24 ].

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.