Comparative Efficacy and Safety of Antibody-Drug Conjugates Versus Standard Chemotherapy in Metastatic Breast Cancer: A Comprehensive Systematic Review and Meta-Analysis.

Cureus · 2025 · PMC12765512 · PMID 41492592

Europe PMC DOI

hedged sentence

0.0800

closest p · 1.6× alpha

0.0800

boldest claim

The sentences

showed a trendp = 0.08so close (0.05 < p ≤ 0.1)

In terms of safety, ADCs showed a trend toward fewer grade ≥3 Aes (OR = 0.68, p = 0.08), supporting their improved tolerability compared with conventional chemotherapy, and Diéras et al.

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