Although the hazard ratio (HR 7.07; 95% CI, 0.74–68.01; P = 0.090) did not reach statistical significance, it suggests a possible trend toward increased risk with denosumab [ 3 , 4 ].
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Asian Federation of Osteoporosis Societies 2025 consensus on atypical femoral fractures in patients with osteoporosis.
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The sentences
Although the hazard ratio (HR 7.07; 95% CI, 0.74–68.01; P = 0.090) did not reach statistical significance, it suggests a possible trend toward increased risk with denosumab [ 3 , 4 ].