GASDERMIN D-mediated pyroptosis as a therapeutic target in TAU-dependent frontotemporal dementia mouse model.

J Biomed Sci · 2026 · PMC12766953 · PMID 41486173

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highly significantno p-value reported

Additionally, we observed a highly significant reduction in the levels of the pro-inflammatory cytokines Il6 and Cxcl5 (Supplementary Figure S2F and G, respectively).

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did not reach statistical significanceno p-value reported

In the case of Tnfa , Cxcr3 , and Olr1 expression levels, we also detected a decrease, although it did not reach statistical significance (Supplementary Figure S2H-J, respectively).

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