Gut-Bone Axis Mediates Exercise Modality-Dependent Suppression of Inflammatory Osteoclastogenesis in Ovariectomy-Induced Bone Loss.

Mediators Inflamm · 2025 · PMC12767480 · PMID 41498043

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showed a trendno p-value reported

Both HIIT and MICE showed a trend of promoting the expression of RUNX2 in the growth plate and OCN in the marrow cavity of OVX mice, but the differences were not statistically significant (for IHC score of RUNX2: OVX‐HIIT vs.

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a nonsignificant trendno p-value reported

While both HIIT and MICE showed a nonsignificant trend toward enhancing osteoblast activity, only MICE counteracted OVX‐induced osteoclast hyperactivity.

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