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Continued Versus Interrupted Oral Anticoagulation During Transcatheter Aortic Valve Replacement in Patients With Atrial Fibrillation: A Meta-Analysis.

Am J Ther · 2026 · PMC12767628 · PMID 40396898

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However, it is crucial to note that this difference did not reach statistical significance in major bleeding events [11.1% and 8.9% (risk difference, 2.2 percentage points; 95% CI, −1.8 to 6.3)], suggesting that the observed trend may be influenced by study's limitation and biases rather than a definitive difference in risk.

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