Distribution and prognostic significance of myelotoxicity in newly diagnosed glioblastoma in a real-life cohort: Time to treat more aggressively?

Neurooncol Adv · 2025 · PMC12768505 · PMID 41497453

Europe PMC DOI

hedged sentences

0.0540

closest p · 1.1× alpha

0.0540

boldest claim

The sentences

a trend toward significancep = 0.054so close (0.05 < p ≤ 0.1)

Subgroup analysis revealed a trend toward significance in the Stupp regimen (p = 0.054) but not in CeTeG (p = 0.101; Figure 1C ).

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did not reach statistical significanceno p-value reported

In contrast, in the absence of myelotoxicity, the MGMT effect was less consistent and in some subgroups did not reach statistical significance, likely due to small sample size.

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