Molecular and functional asymmetry in Cckar-expressing vagal sensory neurons.

While the majority of Cckar + cells were found to co-express Cartpt ( n = 2,213/3,250, 68.1%), the reverse was not true–most Cartpt + cells did not co-express Cckar or Glp1r ( Figure 5E ; n = 6,866/9,387, 73.1%), and differential expression of Cartpt + cells did not reach statistical significance ( Figure 5G ; left, 255.04 ± 24.39; right, 316.09 ± 15.23; p = 0.0598; paired t test).

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As in the previous experiment, we found significant right-biased expression of Cckar + neurons ( Figure 4O ; percent Cckar + , left, 11.86% ± 0.91%; right, 19.60% ± 1.83%; p = 0.0162; paired t test), but differential expression of Chrna3 + did not quite reach statistical significance ( Figure 4P ; left, 19.97% ± 2.28%; right, 24.77% ± 2.51%; p = 0.0661; paired t test).

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