Long-Term Survival Outcomes of NCRT With Surgery vs Surgery With Adjuvant Therapy for ESCC: A Single-Center Prospective Phase 3 Randomized Clinical Trial.

JAMA Netw Open · 2026 · PMC12771256 · PMID 41490111

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did not reach statistical significanceno p-value reported

For grade 3 to 4 hematologic toxic effects, leukopenia (35.6% vs 26.2%; P = .17) and neutropenia (32.2% vs 23.3%; P = .14) were more frequent in the NCRT group, but these differences did not reach statistical significance.

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