Barely Significant
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HLA-DR Matching in Kidney Transplantation: Ethnic Disparities in Clinical Benefit and Policy Implications From a UK Registry Analysis.

Clin Transplant · 2026 · PMC12771550 · PMID 41492942

2
hedged sentences
0.0010
closest p · 0.0× alpha
0.1290
boldest claim

The sentences

highly significantp < 0.001actually significant
For each locus (HLA‐A, ‐B, ‐DR, and ‐DQ), chi‐square testing demonstrated highly significant variation among ethnic groups ( p < 0.001), validating that the observed disparities in mismatch exposure were statistically robust.

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did not reach statistical significancep = 0.129not close (p > 0.1)
Among the Black subgroup, the analysis revealed that donor‐recipient mismatches in the DR category were associated with reduced sub‐distribution hazard ratios (SHRs), specifically, a SHR of 0.693 (95% CI: 0.432, 1.113) for Level 2, however, it did not reach statistical significance ( p = 0.129).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.