Association between proton pump inhibitor use and upper gastrointestinal cancer: A matched case-control study accounting for reverse causation and confounding by indication.

PLoS Med · 2026 · PMC12773814 · PMID 41493925

Europe PMC DOI

hedged sentence

0.0960

closest p · 1.9× alpha

0.0960

boldest claim

The sentences

did not reach statistical significancep = 0.096so close (0.05 < p ≤ 0.1)

The association for lansoprazole was borderline and did not reach statistical significance (aOR 1.26, 95% CI 0.96–1.66, p = 0.096).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.