Barely Significant
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Comparative human and porcine skin permeation profiles of novel metformin lotion formulations.

Sci Rep · 2025 · PMC12775088 · PMID 41326581

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showed a trendno p-value reported
Although no significant differences were observed between HS + PG and HS + Gly, PG showed a trend toward higher epidermal and dermal absorption with less unabsorbed drug remaining.

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