In contrast, PC-3 PIP cells, exhibited an activity-dependent increase in apoptotic populations at activities ≥ 12.5 kBq/mL, though changes did not reach statistical significance ( p > 0.05; Fig. 4 b).
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Cytotoxicity and cell cycle changes in prostate cancer cells with differing PSMA expression and p53 status after treatment with PSMA-targeting radioligand [<sup>212</sup>Pb]Pb-AB001.
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