Grey‐White matter contrast as an early brain pathology marker in Familial Alzheimer's disease

Alzheimers Dement · 2025 · PMC12777538

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closest p · 2.0× alpha

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a negative trendp ≤ 0.1so close (0.05 < p ≤ 0.1)

Lower GWC was associated with closer proximity to symptom onset in both the inferior parietal and supramarginal cortices, with a negative trend ( p ≤ 0.1) for all but one of the ROIs (Figure 2a).

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