Nerinetide Reduces Early Infarct Growth Among Stroke Patients Undergoing EVT Without Intravenous Alteplase.

In 2 adjusted analyses in which probabilities of achieving both ordinal and good outcome were derived from multivariable logistic regression, nerinetide administration failed to reach significance in the ordinal model ( P = 0.113), despite the proportional odds assumption not being rejected ( P = 0.489).

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Differences in unadjusted clinical outcomes in this under‐powered subset of participants (179 of 446 in the full no‐alteplase stratum) failed to reach statistical significance, although a trend toward better outcomes in no‐alteplase patients treated with nerinetide was seen.

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