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An Accessible Platform to Quantify Oxygen Diffusion in Cell-Laden Hydrogels and Its Application to Alginate-Immobilized Pancreatic Beta Cells.

Biotechnol Bioeng · 2026 · PMC12779220 · PMID 41220227

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Although the diffusion coefficient differences between 5% and 2% Manugel did not reach statistical significance, the faster trend observed in the raw data may indicate an effect of the polymer concentration – as would be expected for more tortuous diffusion paths created by polymer chains (Bellich et al. 2011 ; Najdahmadi et al. 2018 ).

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