Global prevalence and incidence of precocious puberty: a systematic review and meta-analysis.

BMC Public Health · 2025 · PMC12781560 · PMID 41331916

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a clear trendno p-value reported

This finding indicated a clear trend toward earlier pubertal timing, which was consistent with current research.

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a slight trendno p-value reported

Until recent 15 to 20 years, some studies have reported a slight trend towards earlier puberty in boys, with a 3-month decline between 1991 and 2008, coinciding with increased luteinizing hormone levels [ 55 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.