Triple probiotic combination effect on metabolic, oxidative stress, and inflammatory parameters in diabetic population: Systematic review and meta-analysis.

World J Exp Med · 2025 · PMC12781632 · PMID 41523772

Europe PMC DOI

hedged sentences

0.0700

closest p · 1.4× alpha

0.0700

boldest claim

The sentences

approached significanceP = 0.07so close (0.05 < p ≤ 0.1)

Supplementation of triple probiotic therapy significantly improved the serum TAC level (MD: +92.55 mmol/L, 95%CI: +40.87 to +144.22; P = 0.0004; Figure 4A ) while it approached significance in case of serum GSH level (MD: +40.55 μmol/L, 95%CI: -3.32 to +84.42; P = 0.07; Figure 4B ) compared to control group.

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marginally significantno p-value reported

Marginally significant heterogeneity was observed for serum GSH level ( I 2 = 53%), while non-significant for serum TAC level.

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