Real-world effectiveness and safety of eculizumab in AQP4-IgG-positive neuromyelitis optica spectrum disorder.

Use of add-on immunosuppressants (steroids or azathioprine) did not show a significant impact on EDSS outcomes, although a near-significant trend was observed for concomitant steroid use after 24 months ( p = 0.05) (Table 2 ).

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