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The Role of Emerging Immune-Inflammatory Indexes in the Preoperative Differentiation of Complicated and Uncomplicated Acute Appendicitis: A Single-Center Retrospective Analysis.

Diagnostics (Basel) · 2025 · PMC12785300 · PMID 41515516

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In histopathological analysis, five indices (NLR, MLR, SII, SIRI, and PIV) remained significantly elevated in patients with wall necrosis or perforation ( p = 0.000–0.019), while PLR did not reach statistical significance.

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